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Test Code LAB1111 Valproic Acid, Total, Plasma or Serum

Additional Codes

Test Name in EPIC EPIC Test Code Mnemonic
VALPROIC ACID LAB1111 VALP

 

Methodology

Particle-Enhanced Turbidimetric Inhibition Immunoassay (PETINIA)

Specimen Requirements

Specimen must be refrigerated until test is performed.

 

Submit only 1 of the following specimens:

 

Preferred:

Specimen Type: Plasma

Container/Tube: Light-green top (lithium heparin gel)

Specimen Volume: 1 mL

Specimen Minimum Volume: 0.5 mL/pediatric: 0.2 mL in a green top MICROTAINER

Collection Instructions:

1. For therapeutic monitoring, draw trough level up to 30 minutes prior to dose. Peak specimen should be drawn 30 minutes after an oral liquid dose or 2 to 8 hours after dose if tablet or capsule is given. If toxicity is suspected, draw level when ordered STAT.

2. Spin down, separate plasma from cells within 2 hours of draw.

3. If plunger filters are used, immediate removal of plasma is indicated unless an air gap can be created between the device and specimen.

Additional Information:

1. Avoid repeated freeze/thaw cycles.

2. If extreme lipemia-use ultracentrifuged specimen.

3. Label specimen appropriately (plasma).


Alternate:

Specimen Type: Serum

Container/Tube: Serum gel

Specimen Volume: 1 mL

Specimen Minimum Volume: 0.5 mL/pediatric: 0.2 mL in a red top MICROTAINER

Collection Instructions:

1. For therapeutic monitoring, draw trough level up to 30 minutes prior to dose. Peak specimen should be drawn 30 minutes after an oral liquid dose or 2 to 8 hours after dose if tablet or capsule is given. If toxicity is suspected, draw level when ordered STAT.

2. Spin down, separate serum from cells within 2 hours of draw.

3. If plunger filters are used, immediate removal of serum is indicated unless an air gap can be created between the device and specimen.

Additional Information:

1. Avoid repeated freeze/thaw cycles.

2. If extreme lipemia-use ultracentrifuged specimen.

3. Label specimen appropriately (serum).

Specimen Transport Temperature

Refrigerate 2 days (48 hours)/Frozen 5 days OK/Ambient 8 hours OK

Day(s) Test Set Up

Monday through Sunday

Reference Values

Therapeutic concentration: 50-100 µg/mL

Test Classification and CPT Coding

80164

Performing Laboratory

Chemistry-

Central Region: St. Joseph's Medical Center Lab

East Region: Deer River Hospital Lab, Sandstone Hospital Lab, SMDC Clinical Lab, St. Mary's Hospital - Superior Lab, Virginia Hospital Lab

West Region: Fargo Hospital Lab, Fosston Hospital Lab, St. Mary's - Detroit Lakes Hospital Lab