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Test Code FBART Bartonella Antibody Panel, IFA CSF


Specimen Required


Specimen Type: Spinal Fluid

Sources: CSF

Container/Tube: Sterile container

Specimen Volume: 1 mL

Collection Instructions: Collect 1 mL of spinal fluid (CSF). Ship refrigerate


Profile Information

Test ID Reporting Name Available Separately Always Performed
FBHEN Bartonella Henselae Ab Panel (CSF) No Yes
FBARQ Bartonella Quintana Ab Panel (CSF) No Yes

Method Name

Immunofluorescence Assay (IFA)

Reporting Name

Bartonella Antibody Panel, IFA (CSF)

Specimen Type

CSF

Specimen Minimum Volume

0.1 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  7 days

Reject Due To

Hemolysis

NA

Thawing

NA

Lipemia

NA

Icterus

NA

Other

Specimens other than CSF

Reference Values

REFERENCE RANGE: <1:1

  

INTERPRETIVE CRITERIA:

<1:1 Antibody Not Detected

≥ 1:1 Antibody Detected

 

Infection with Bartonella henselae has been associated with cat scratch disease, bacillary angiomatosis, peliosis hepatis and febrile bacteremia syndrome. Infection with Bartonella quintana has been associated with trench fever and bacillary angiomatosis in both HIV positive and negative individuals.

 

IgG crossreactivity between B. henselae and B. Quintana may occur at any titer; however, the infecting species will typically have the higher IgG titer. Crossreactivity of IgM between the two species is limited and typically is not seen.

  

Diagnosis of infections of the central nervous system can be accomplished by demonstrating the presence of intrathecally-produced specific antibody. However, interpreting results is complicated by low antibody levels found in CSF, passive transfer of antibody from blood, and contamination via bloody taps.

Day(s) and Time(s) Performed

Monday through Saturday

Analytic Time

1 - 3 days

Performing Laboratory

Quest Diagnostics Infectious Disease

Test Classification

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics Infectious Disease. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

CPT Code Information

86611 x 4

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FBART Bartonella Antibody Panel, IFA (CSF) In Process

 

Result ID Test Result Name Result LOINC Value
Z0694 B. Quintana IgG 23974-9
Z0693 B. Henselae IgG 23954-1
Z0474 B. Henselae IgM 23955-8
Z0475 B. Quintana IgM 23975-6