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Test Code CH8BI Chromogenic Factor VIII Inhibitor Bethesda Profile Interpretation


Specimen Required


 


Useful For

Interpretation of CHF8P / Chromogenic Factor VIII Inhibitor Bethesda Profile, Plasma

 

Detecting the presence and titer of a specific factor inhibitor directed against coagulation factor VIII

 

This test is not useful for detecting the presence of inhibitors directed against other clotting factors and will not detect the presence of lupus anticoagulants.

Method Name

Only orderable as part of a profile. For more information see CHF8P / Chromogenic Factor VIII Inhibitor Bethesda Profile, Plasma.

 

Medical Interpretation

Reporting Name

Chromogenic FVIII Inhibitor Interp

Specimen Type

Plasma Na Cit

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Na Cit Frozen 14 days

Clinical Information

Factor VIII (FVIII) inhibitors are IgG antibodies directed against coagulation FVIII that typically result in development of potentially life-threatening hemorrhage. These antibodies may be alloimmune: developing in patients with congenital FVIII deficiency (hemophilia A) in response to therapeutic infusions of factor VIII concentrate or autoimmune: occurring in patients without hemophilia (not previously factor VIII deficient) either spontaneously or during pregnancy or in association with autoimmune diseases.

Reference Values

Only orderable as part of a profile. For more information see CHF8P / Chromogenic Factor VIII Inhibitor Bethesda Profile, Plasma.

 

An interpretive report will be provided.

Interpretation

The interpretive report will include assay information, background information, and conclusions based on the test results.

Cautions

Contamination with excess heparin and hemodilution due to improper specimen collection through an intravenous access device or collection above a running intravenous fluid line may cause spurious results.

Method Description

A coagulation expert (clinician or hematopathologist) reviews the laboratory data, and an interpretive report is issued.

Day(s) Performed

Monday through Friday

Report Available

3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

Not Applicable

CPT Code Information

85390-26

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CH8BI Chromogenic FVIII Inhibitor Interp 95122-8

 

Result ID Test Result Name Result LOINC Value
606844 Chromogenic FVIII Inhibitor Interp 95122-8
606865 Reviewed by 18771-6