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Test Code DEXT Dermatopathology Consultation, Wet Tissue


Ordering Guidance


This test is only for a dermatopathology wet tissue consultation. For a dermatologic consultation on paraffin embedded tissue and slides, order PATHC / Pathology Consultation.



Shipping Instructions


Attach the green "Attention Pathology" address label (T498) to the outside of the transport container before putting into the courier mailer.



Necessary Information


All requisition and supporting information must be submitted in English.

 

Each of the following items is required:

1. All requisitions must be labeled with:

-Patient name, date of birth and medical record number

-Name and phone number of the referring pathologist or ordering physician

-Anatomic site and collection date

2. A brief patient history is essential to achieve a consultation fully relevant to the ordering clinician’s needs.

3. Preliminary diagnosis or differential diagnosis

4. Clinical and/or dermoscopic images should be included if available. Submit with the request via Epic Care Everywhere, Mayo Clinic Image Share, or external storage device.



Specimen Required


Supplies: Dermatopathology Media (T101)

Sources: Skin or oral mucosa

Container/Tube: Screw-capped container or vial containing 10% formalin

Specimen Volume: Entire specimen

Collection Instructions: For scalp biopsies: when the differential diagnosis includes a scarring alopecia, 2 separate 4-mm punch biopsies are recommended (1 for vertical and 1 for horizontal sections). If a single scalp biopsy is received with the clinical diagnosis of a scarring alopecia, the specimen will be processed with horizontal sections.

Additional Information: STAT requests are not accepted for this test.


Useful For

Histologic diagnosis and differential diagnosis of cutaneous diseases

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
LEV2P Level 2 Gross and microscopic No No
LEV3P Level 3 Gross and microscopic No No
LEV4P Level 4 Gross and microscopic No No

Testing Algorithm

When this test is ordered, 1 of the 3 reflex tests will be performed at an additional charge. Appropriate additional stains and other ancillary testing may also be performed, at an additional charge, to determine a diagnosis.

 

For more information see Pathology Consultation Ordering Algorithm

Method Name

Formalin-fixed tissues: Process/Embed

Serial sections: Hematoxylin and Eosin Stain/Light Microscopy

Reporting Name

Dermatopathology Consult

Specimen Type

Tissue

Specimen Minimum Volume

Size needed depends on diagnosis and size of lesion.

Specimen Stability Information

Specimen Type Temperature Time Special Container
Tissue Ambient

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Clinical Information

Dermatopathology involves histologic examination of skin biopsy and oral mucosal specimens.

Reference Values

Diagnosis and description of microscopic findings

Interpretation

Histologic diagnosis is based primarily on interpretation of hematoxylin and eosin-stained sections. Special histochemical stains, such as alcian blue, Giemsa, or periodic acid-Schiff, may be necessary in some cases.

 

Interpretation is based on evaluation of patterns including architectural and cytologic details, which are included in a microscopic description.

Cautions

Specific diagnosis may require correlation with clinical information.

Method Description

Formalin-fixed, paraffin-embedded skin biopsy sections are stained and interpreted utilizing a bright-field microscope.(Elder DE, Elenitsas R, Rosenbach M, Murphy GF, Ruben AL, Xu X, eds. Lever's Histopathology of the Skin. 11th ed. Lippincott Williams and Wilkins; 2019)

Day(s) Performed

Monday through Friday

Report Available

3 to 5 days: Cases requiring additional material or ancillary testing may require additional time.

Specimen Retention Time

Indefinitely

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

88302 (if appropriate)

88304 (if appropriate)

88305 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DEXT Dermatopathology Consult 60570-9

 

Result ID Test Result Name Result LOINC Value
71139 Interpretation 33746-9
71140 Participated in the Interpretation No LOINC Needed
71141 Report electronically signed by 19139-5
71142 Addendum 35265-8
71143 Gross Description 22634-0
71582 Disclaimer 62364-5
71854 Case Number 80398-1

Test Classification

Not Applicable