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HelpTest Code LAB19 Cholesterol, HDL, Plasma or Serum
Additional Codes
| Test Name in EPIC | EPIC Test Code | Mnemonic |
|---|---|---|
| HDL CHOLESTEROL | LAB19 | HDL |
Useful For/Utility
Useful for measurement of serum high-density lipoprotein concentrations for managing atherosclerotic cardiovascular disease risk.
Methodology
Accelerator Selective Detergent
Clinical Information
Plasma lipoproteins are spherical particles containing varying amounts of cholesterol, triglycerides, phospholipids, and proteins. Phospholipids, free cholesterol, and proteins constitute the outer surface of the lipoprotein particle, while the inner core contains mostly esterified cholesterol and triglyceride. These particles serve to solubilize and transport cholesterol and triglyceride in the bloodstream.The relative proportions of protein and lipid determine the density of these lipoproteins and provide a basis on which to begin their classification.1 The classes are: chylomicron, very-low-density lipoprotein (VLDL), low-density lipoprotein (LDL), and high-density lipoprotein (HDL). Numerous clinical studies have shown that the different lipoprotein classes have very distinct and varied effects on coronary heart disease risk.2The principle role of HDL cholesterol in lipid metabolism is the uptake and transport of cholesterol from peripheral tissues to the liver through a process known as reverse cholesterol transport (a proposed cardioprotective mechanism).3 Low HDL cholesterol levels are strongly associated with an increased risk of coronary heart disease.4 -7Hence, the determination of serum HDL cholesterol is a useful tool in identifying high-risk patients. The Adult Treatment Panel of the National Cholesterol Education Program (NCEP) recommends that in all adults 20 years of age and over, a fasting lipoprotein profile (total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride) should be obtained once every five years to screen for coronary heart disease risk.8
Specimen Requirements
Submit only 1 of the following specimens:
Preferred:
Specimen Type: Plasma
Container/Tube: Light-green top (lithium heparin gel)
Specimen Volume: 1 mL
Specimen Minimum Volume: 0.5 mL
Collection Instructions:
1. Separate plasma from cells within 2 hours of draw.
2. If plunger filters are used, immediate removal of plasma is indicated unless an air gap can be created between the device and specimen.
Additional Information:
1. Avoid repeated freeze/thaw cycles.
2. Label specimen appropriately (plasma).
Alternate:
Specimen Type: Serum
Container/Tube: Serum gel
Specimen Volume: 1 mL
Specimen Minimum Volume: 0.5 mL
Collection Instructions:
1. Separate serum from cells within 2 hours of draw.
2. If plunger filters are used, immediate removal of serum is indicated unless an air gap can be created between the device and specimen.
Additional Information:
1. Avoid repeated freeze/thaw cycles.
2. Label specimen appropriately (serum).
Specimen Transport Temperature
Refrigerate 5 days/Ambient 8 hours OK/Frozen OK
Day(s) Test Set Up
Monday through Sunday
Performing Laboratory
Chemistry -
St. Joseph's - Baxter Clinic Lab, St. Joseph's - Brainerd Clinic Lab, St. Joseph's Medical Center Lab
Ashland Clinic Lab, Deer River Hospital Lab, Ely Clinic Lab, Hayward Clinic Lab, Hibbing Clinic Lab, International Falls Clinic Lab, Northern Pines Lab, Moose Lake Hosptial Lab, Sandstone Hospital Lab, SMDC Clinical Lab, Spooner Clinic Lab, St. Mary's Hospital - Superior Lab, Virginia Hospital Lab
Ada Hospital Lab, Fargo Hospital Lab, Fosston Hospital Lab, Holy Trinity Hospital Lab, Park Rapids Clinic Lab, South University Clinic Lab, St. Mary's - Detroit Lakes Hospital Lab
Test Classification and CPT Coding
83718
Reference Values
The National Lipid Association and the National Cholesterol Education Program (NCEP) have set the following guidelines for lipids (total cholesterol, triglycerides, high-density lipoprotein [HDL] cholesterol, low-density lipoprotein [LDL], and non-HDL cholesterol) in adults 18 years old and older:
Males: ≥ 40 mg/dLR
Females: ≥ 50 mg/dL
The Expert Panel on Intergrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents has set the following guidelines for lipids (total cholesterol, triglycerides, high-density lipoprotein [HDL] cholesterol, low-density lipoprotein [LDL], and non-HDL cholesterol) in children up to the age of 17:
≥ 45 mg/dL