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Test Code LAB2C82C9 CYP2C8, CYP2C9, and CYP2C cluster

Additional Codes

Test Name in EPIC EPIC Test Code Mnemonic ARUP Test ID
CYP2C8, CYP2C9, and CYP2C cluster LAB2C82C9 2C8/2C9 3001501

 

Clinical Information

Use to assess genetic risk of abnormal drug metabolism for drugs metabolized by enzymes coded by CYP2C8, CYP2C9, and the 2C cluster variant (rs12777823).

Useful For/Utility

May aid in drug selection and dose planning for drugs metabolized by enzymes coded by CYP2C8, CYP2C9 and the 2C cluster variant (rs12777823).

Specimen Type


Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B).

Specimen Required

Collect    
Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B).

Specimen Preparation    
Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature    
Refrigerated.

Unacceptable Conditions    
Plasma or serum. Specimens collected in sodium heparin or lithium heparin. Frozen specimens in glass collection tubes.

Remarks    
Stability    
Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month

Specimen Stability Information

Ship Refrigerated

Day(s) Performed

Varies

Reported in 5-10 days

CPT Code Information

81227; 81479

LOINC Code Information

Component Chart Name LOINC
CYP2C9 Phenotype 79716-7
2C8/2C9 Specimen 66746-9
CYP2C8 Genotype 78972-7
CYP2C9 Genotype 46724-1
2C8/2C9 Interpretation 50398-7
CYP2C8 Phenotype 81259-4
CYP2C Cluster Geno 101785-4
CYP2C Cluster Pheno 81259-4
EER CYP2C8 CYP2C9 CYP2C Cluster 11526-1

 

Performing Laboratory

ARUP Laboratories

Method and Method Description

Polymerase Chain Reaction (PCR)/Fluorescence Monitoring