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Test Code LAB304 Theophylline, Plasma or Serum

Additional Codes

Test Name in EPIC EPIC Test Code Mnemonic
THEOPHYLLINE LAB304 THEO

 

Methodology

Chemiluminescent Microparticle Immunoassay (CMIA)

Specimen Requirements

Draw specimens according to following schedule:

Oral Loading Dose Draw Time
NICU 4 hours post dose
PICU (liquid oral) 2 hours post dose
PICU (oral tablet/capsule) 3 to 4 hours post dose
Adult (liquid [fast release] or sustained release tablet/ capsule:  routine therapeutic monitoring) draw a trough level
Adult (peak level) 4 to 8 hours post dose
   
Intravenous Loading Dose Draw Time
NICU 4 hours after dose is infused
Adult 4 to 8 hours after start of infusion or rate changes*
*A level may need to be drawn 30 minutes after loading dose to see if additional loading dose is needed.
If toxicity is suspected, draw level when ordered STAT.

Specimen must be refrigerated until test is performed.

 

Submit only 1 of the following specimens:

 

Preferred:

Specimen Type: Plasma

Container/Tube: Light-green top (lithium heparin gel)

Specimen Volume: 1 mL

Specimen Minimum Volume: 0.5 mL

Collection Instructions: Hemolyzed specimen is not acceptable. Spin down, separate plasma from cells within 2 hours of draw.

Additional Information:

1. Avoid repeated freeze/thaw cycles.

2. If extreme lipemia-use ultracentrifuged specimen.

3. Label specimen appropriately (plasma).

Alternate:

Specimen Type: Serum

Container/Tube: Serum gel

Specimen Volume: 1 mL

Specimen Minimum Volume: 0.5 mL

Collection Instructions: Hemolyzed specimen is not acceptable. Spin down, separate serum from cells within 2 hours of draw.

Additional Information:

1. Avoid repeated freeze/thaw cycles.

2. If extreme lipemia-use ultracentrifuged specimen.

3. Label specimen appropriately (serum).

Specimen Transport Temperature

Refrigerate 5 days /Frozen OK/Ambient 48 hours OK

Day(s) Test Set Up

Monday through Sunday

Performing Laboratory

Chemistry-

 

East Region: SMDC Clinical Lab

West Region: Fargo Hospital Lab

Test Classification and CPT Coding

80198

Reference Values

10-20 µg/mL