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Test Code LAB3588 C-Reactive Protein (CRP) High Sensitivity, Cardiac Risk, Plasma or Serum

Additional Codes

Test Name in EPIC EPIC Test Code Mnemonic
CRP HI SENS CARD LAB3588 CRPHS

 

Useful For/Utility

Useful as an aid in identification and stratification of individuals at risk for cardiovascular disease. When used in conjunction with traditional clinical laboratory evaluation of acute coronary syndromes, Cardiac CRP may be useful as an independent marker of prognosis for recurrent events, in patients with stable coronary disease or acute coronary syndrome.

Methodology

Turbidimetric/Immunoturbidimetric

This test is recommended for cardiovascular risk assessment only.

Clinical Information

Studies have shown that measurement of CRP using a sensitive assay is a strong independent predictor of risk for future cardiovascular and peripheral vascular disease.1 CRP measurements have also been shown to add to the predictive value of other markers used to assess the risk of cardiovascular and peripheral vascular disease.2-4 Elevated CRP values determined by Cardiac CRP may be indicative of the prognosis of individuals with acute coronary syndromes, and may be useful in the management of such individuals.

Specimen Requirements

Submit only 1 of the following specimens:

 

Preferred:

Specimen Type: Plasma

Container/Tube: Light-green top (lithium heparin gel)

Specimen Volume: 1 mL

Specimen Minimum Volume: 0.5 mL

Collection Instructions:

1. Separate plasma from cells within 2 hours of draw.

2. If plunger filters are used, immediate removal of plasma is indicated unless an air gap can be created between the device and specimen.

Additional Information: Label specimen appropriately (plasma).


Alternate:

Specimen Type: Serum

Container/Tube: Red top with clot activator or serum gel

Specimen Volume: 1 mL

Specimen Minimum Volume: 0.5 mL

Collection Instructions:

1. Separate serum from cells within 2 hours of draw.

2. If plunger filters are used, immediate removal of serum is indicated unless an air gap can be created between the device and specimen.

Additional Information: Label specimen appropriately (serum).

Specimen Transport Temperature

Refrigerate 5 days/Ambient 8 hours OK/Frozen OK

Day(s) Test Set Up

Monday through Sunday

Performing Laboratory

Chemistry -

St. Joseph's Medical Center Lab

SMDC Clinical Laboratory

Fargo Hospital

Test Classification and CPT Coding

86141

Reference Values

0-3 mg/L

RELATIVE RISK CATEGORIES FOR CORONARY HEART DISEASE

Low: 0-1 mg/L

Average: 1-3 mg/L

High: >3.0 mg/L

 

Values >14 mg/L may indicate an underlying inflammaory condition, and this result should not be used to assess coronary risk.  Repeat testing after resolution of inflammatory condition is suggested.