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Test Code LAB5419 Protein, Total, 12 Hour, Night, Urine

Additional Codes

Test Name in EPIC EPIC Test Code Mnemonic
PROT UR 12H NITE LAB5419 U12NT

 

Useful For/Utility

Evaluation of renal disease

Screening for monoclonal gammopathy

Screening for postural (orthostatic) proteinuria

In select clinical situations, collection of a 12-hour specimen may allow more rapid detection of proteinuria states (eg, screening pregnant patients for preeclampsia)

Methodology

Benzethonium Chloride

Clinical Information

The role of the renal system in the conservation of plasma proteins has been recognized for some time. Under normal physiological conditions small molecular weight proteins, such as insulin, pass through the glomeruli in relatively large amounts. Intermediate size proteins, such as transferrin and albumin, also pass through in relatively small amounts. Most of these proteins are reabsorbed in the renal tubules.2, 3Most CSF protein originates by diffusion from plasma across the blood-CSF barrier. Elevated levels occur as a result of increased permeability of the blood-CSF barrier or with increased local synthesis of immunoglobulins.

Specimen Requirements

Specimen Type: Urine, 12 hour

Container/Tube: Aliquot tube

Specimen Volume: 5 mL

Specimen Minimum Volume: 2 mL

Collection Instructions: 

1. No preservative. Mix well before taking aliquot.

2. See Urine Collection in Special Instructions for timed urine collection instructions.

Additional Information: Starting and ending times of collection and 12 hour volume are required.

 

Performing Laboratory

Measure 12 hour volume. Enter volume and hours of collection into LIS. If specimen is cloudy, spin and separate supernatant. Refrigerate specimen until analysis is performed.

Specimen Transport Temperature

Refrigerate 5 days/Frozen OK/Ambient 24 hours OK

Day(s) Test Set Up

Monday through Sunday

Performing Laboratory

Chemistry-

St. Joseph's - Baxter Clinic Lab, St. Joseph's - Brainerd Clinic Lab, St. Joseph's Medical Center Lab

 Ashland Clinic Lab, Deer River Hospital Lab, Ely Clinic Lab, Hibbing Clinic Lab, International Falls Clinic Lab, Moose Lake Hosptial Lab,SMDC Clinical Lab, St. Mary's Hospital - Superior Lab, Virginia Hospital Lab

Fargo Hospital Lab, St. Mary's - Detroit Lakes Hospital Lab

Test Classification and CPT Coding

84156

Reference Values

No established reference values

Special Instructions