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Test Code LABCJDPRION Prion Marker for Creutzfedt-Jakob Disease, CSF

Important Note

The first 2 mL of CSF that flows from the tap should be discarded.

May aid in the diagnosis of Creutzfeldt-Jakob disease (CJD). This test uses qualitative real-time quaking-induced conversion to identify the causative agent of CJD, and also includes indirect markers of neurodegenerative disease. 

Patient must be 12 years of age or older.

Additional Codes

Test Name in Epic Epic Test Code Mnemonic ARUP Test ID
PRION MARKER FOR CREUTZFEDT-JAKOB DISEASE, CSF LABCJDPRION PRION 3019310

 

Performing Laboratory

ARUP Forward/ National Prion Disease Pathology Surveillance 
Center
2085 Adelbert Road, Room 419
Cleveland, OH 44106
 

Specimen Type

CSF

Specimen Required

2 mL CSF

Patient must be 12 years of age or older.

The first 2 mL of CSF that flows from the tap should be discarded. Transfer 2 mL CSF to ARUP standard transport tubes or other polypropylene tubes, taking care to avoid blood contamination from the tap. Freeze at -20 within 20 minutes of collection. (Min: 1 mL)

Specimen Stability Information

CRITICAL FROZEN

Method and Method Description

Quantitative Enzyme-Linked Immunosorbent Assay (ELISA) / Qualitative Real-Time Quaking-Induced Conversion

Day(s) Test Set Up

Varies

Reported in 8-11 days

CPT/LOINC

86317 x2; 0035U

Component Chart Name LOINC
Prion Markers, Specimen Condition 93047-9
Prion Markers, RT-QuIC 101662-5
Prion Markers, Total tau Protein 101649-2
Prion Markers, 14-3-3 Gamma 27072-8
Likelihood of Prion Disease 97503-7
Reviewed/Approved, Prion Markers 59465-5