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Test Code LABDERMPOLY Dermatomyositis and Polymyositis Panel

Additional Codes

Test Name in EPIC EPIC Test Code Mnemonic ARUP Test Code
Dermatomyositis and Polymyositis Panel LABDERMPOLY Combi Pan2 3018866

 

Useful For/Utility

May be useful for the evaluation of patients with progressive proximal muscle weakness and/or cutaneous manifestations suggestive of dermatomyositis and/or associated connective tissue disease.

Methodology

Qualitative Immunoprecipitation / Semi-Quantitative Multiplex Bead Assay / Qualitative Immunoblot / Semi-Quantitative Indirect Fluorescent Antibody (IFA) / Qualitative Particle-Based Multianalyte Technology (PMAT)

Specimen Requirements

Serum SST

Specimen Transport Temperature

Ship Refrigerated

Day(s) Test Set Up

Sunday -Saturday

Test Classification and CPT Coding

Antibodies:  PL-7, PL12, EJ, OJ, SRP, Jo-1, Mi-2, P155/140, SAE1, MDA5, NXP2, TIF1-gamma, ANA, Ha, Ks, Zo

83516 x 11

84182 x3 

86235

86039

 

Reference Values

Jo-1 Antibody, IgG    29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive

Zo (phenylalanyl-tRNA synthetase) Ab    Negative
     Ks (asparaginyl-tRNA synthetase) Ab    Negative
     Ha (tyrosyl-tRNA synthetase) Ab    Negative
     TIF-1 gamma (155 kDa) Ab    Negative
     NXP2 (Nuclear matrix protein-2) Ab    Negative
     MDA5 (CADM-140) Ab    Negative
     SAE1 (SUMO activating enzyme) Ab    Negative
     Antinuclear Antibody (ANA), HEp-2, IgG    Less than 1:80
     OJ (isoleucyl-tRNA synthetase) Antibody    Negative
     SRP (Signal Recognition Particle) Ab    Negative
     EJ (glycyl-tRNA synthetase) Antibody    Negative
     P155/140 Antibody    Negative
     PL-12 (alanyl-tRNA synthetase) Antibody    Negative
     PL-7 (threonyl-tRNA synthetase) Antibody    Negative
     Mi-2 (nuclear helicase protein) Antibody    Negative
     Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG    40 AU/mL or less