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HelpTest Code LABFADBC Adenosine Deaminase, RBC
Additional Codes
| Test Name in EPIC | EPIC Test Code | Mnemonic | Mayo Test ID |
|---|---|---|---|
| Adenosine Deminase, RBC | LABFADBC | FADBC | FADBC |
Specimen Required
Container/Tube: Lavender top (EDTA), pink top (K2 EDTA), or green top (sodium or lithium heparin)
Specimen Volume: 1 mL
Collection Instructions: Send 1 mL whole blood refrigerate.
Method Name
Kinetic Spectrophotometry
Reporting Name
Adenosine Deaminase RBCSpecimen Type
Whole Blood EDTASpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood EDTA | Refrigerated (preferred) | 15 days |
| Ambient | 15 days |
Reject Due To
| Hemolysis | Reject |
Reference Values
400 - 900 mU/g Hb
Interpretation
Affected individuals have less than 1% of normal adenosine deaminase (ADA) catalytic activity in red cell hemolysates. ADA deficiency is the cause of 20% to 30% of severe combined immunodeficiency (SCID) cases. Heterozygotes cannot be identified by this test.
Day(s) Performed
Sunday, Tuesday, Thursday
Report Available
3 to 8 daysPerforming Laboratory
ARUP LaboratoriesTest Classification
This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.CPT Code Information
84311
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FADBC | Adenosine Deaminase RBC | 47549-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| FADBC | Adenosine Deaminase RBC | 47549-1 |
Useful For
As a marker of severe combined immunodeficiency (SCID)
Clinical Information
Adenosine deaminase (ADA) deficiency is an autosomal recessive disorder of purine metabolism primarily affecting lymphocyte development, viability, and function. Lack of ADA allows deoxyadenosine to accumulate and kill lymphocytes.
Cautions
If the patient has been recently transfused, adenosine deaminase (ADA) deficiency may be masked; interpret results with caution.