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HelpTest Code LABPORFECES Porphyrins, Fecal
Additional Codes
| Test Name in EPIC | EPIC Test Code | Mnemonic | ARUP Test ID |
|---|---|---|---|
| Porphyrins, Fecal Random | LABPORFECES | POR FECES | 0099824 |
Performing Laboratory
ARUP
Specimen Type
Random Stool
Specimen Required
Transport 5 g stool. (Min: 1 g)
Specimen Stability Information
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Protect from light during collection, storage, and shipment. Freeze specimen and wrap in foil immediately after collection.
Method and Method Description
Quantitative High Performance Liquid Chromatography (HPLC)
Useful For/Utility
Distinguish among acute intermittent porphyria (AIP), variegate porphyria (VP), and hereditary coproporphyria (HCP)
Day(s) Test Set Up
Monday - reported in 2-8 Days
LOINC
CPT 84126
Porphyrin Fecal Interpretation 14884-1
Protoporphyrin, Feces 29267-2
Coproporphyrin, Feces 29266-4
Interpretation
This test is useful for differentiation of acute porphyrias following a positive porphobilinogen (PBG), or diagnosis or strong suspicion of acute porphyria. Fecal porphyrin excretion usually is not elevated in acute intermittent porphyria (AIP), but massive increases of fecal coproporphyrin are seen in hereditary coproporphyria (HCP). Fecal protoporphyrin and coproporphyrin excretion is increased in variegate porphyria (VP).
This fecal porphyrins assay is not a screening test. Total porphyrins are not measured.
For additional information, access the Porphyrias topic in ARUP Consult (arupconsult.com).
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes
Reported as Positive or Negative
Reference Interval
Coproporphyrin, Feces 0-45 nmol/g dry weight
Protoporphyrin, Feces 0-100 nmol/g dry weight
Specimen Stability
Critical Frozen 3 Weeks
Reject Due To
Complete timed collections (24-72 hour). Specimens stored in one gallon cans or other large containers. Liquid stool