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HelpTest Code LABRVPC Respiratory Pathogen Panel, Molecular Detection
Additional Codes
| Test Name in EPIC | EPIC Test Code | Mnemonic |
|---|---|---|
| RESPIRATORY PATHOGEN PANEL, MOLECULAR DETECTION | LABRVPC | RVPC |
Methodology
Polymerase chain reaction (PCR) utilizing a qualitative nucleic acid multiplex test
Includes the following respiratory pathogens: Adenovirus, Bordetella parapertussis (IS1001), Bordetella pertussis (ptxP), Chlamydia pneumoniae, Coronavirus (229E, OC43, NL63, HKU1), Human Metapneumovirus, Human Rhinovirus/Enterovirus, Influenza A (including subtypes H1, H1 2009, and H3), Influenza B, Mycoplasma pneumoniae, Parainfluenza Virus (types 1-4), Respiratory Syncytial Virus and SARS-COV-2.
Specimen Requirements
Specimen Type: Nasopharyngeal swab-nylon flocked preferred
Container/Tube: Viral transport media (VTM), or saline
Specimen Volume: Nylon flocked swab preferred
Collection Instructions:
1. Collect specimen using mini-tipped culture swab.
2. Carefully insert the swab into the nostril that presents the most secretion under visual inspection.
3. Keep the swab near the septum floor of the nose while gently pushing the swab into the posterior nasopharynx.
4. Rotate swab several times and remove it from the nasopharynx.
5. Return swab to viral transport media if available or to pre-moistened transport tube. Dry swab is not acceptable.
Additional Information:
1. Label tubes with patient's name (first and last), date and actual time of collection, and source/type of specimen.
Specimen Transport Temperature
Refrigerate 3 days/Frozen -70°C 30 days OK/Ambient NO
Day(s) Test Set Up
Monday through Sunday
Performing Laboratory
| Minnesota | North Dakota |
|---|---|
| SMDC Clinical Lab (Duluth) | Fargo Hospital |
| St. Joseph's Medical Center (Brainerd) |
Test Classification and CPT Coding
Test Classification:
This test is FDA approved for the detection and identification of multiple respiratory virus nucleic acids in nasopharyngeal swabs.
CPT Code:
0202U
Reference Values
Negative (reported as positive or negative)
Special Instructions
Clinical Info
|
Organism (abbreviation) |
Classification (Genome type) |
Season of Highest Incidence(a) |
Most Commonly Infected Demographic |
|
Adenovirus (AdV) |
Adenovirus (DNA) |
Late winter to early summer |
All ages, immunocompromised |
|
Bordetella parapertussis |
Bacterium (DNA) |
No peak season |
All ages |
|
Bordetella pertussis |
Bacterium (DNA) |
No peak season |
All ages |
|
Chlamydophila pneumoniae |
Bacterium (DNA) |
No peak season |
Older children, young adults, immunocompromised |
|
Coronavirus (CoV) 229E,HKU1, NL63, OC43 |
Coronavirus (RNA) |
Winter, spring |
Children, adults |
|
Enterovirus (EV) |
Picornavirus(RNA) |
Summer, early fall |
All ages |
|
Human Rhinovirus (HRV) |
Picornavirus (RNA) |
Fall, spring |
All ages |
|
Human Metapneumovirus (hMPV) |
Paramyxovirus (RNA) |
Winter, early spring |
Children |
|
Influenza A (Flu A) (subtypes H1, H1-2009, and H3) |
Orthomyxovirus (RNA)
|
Winter |
All ages, 5-20 % of US population(b) |
|
Influenza B (Flu B) |
Orthomyxovirus (RNA) |
Winter |
All ages, 5-20 % of US Population(b) |
|
Mycoplasma pneumoniae |
Bacterium (DNA) |
Outbreaks most common in summer, outbreak periodicity 4 – 7 years |
Older children, young adults |
|
Parainfluenza Virus 1 (PIV1) |
Paramyxovirus (RNA) |
Fall, periodicity of 1-2 years |
Infants, young children, immunocompromised |
|
Parainfluenza Virus 2 (PIV2) |
Paramyxovirus (RNA) |
Fall, periodicity of 1-2 years |
Infants, young children, immunocompromised |
|
Parainfluenza Virus 3 (PIV3) |
Paramyxovirus (RNA) |
Spring, summer |
Infants, young children, Immunocompromised |
|
Parainfluenza Virus 4 (PIV4) |
Paramyxovirus (RNA) |
Unknown |
All ages |
|
Respiratory Syncytial Virus (RSV) |
Paramyxovirus (RNA) |
Winter, varies by location |
Children, older adults
|
|
SARS-CoV-2 |
Coronavirus (RNA) |
Novel pandemic Coronavirus |
All ages |
(a) Based on North American seasons
(b) During annual Influenza epidemics, 5-20% of the population is affected with upper respiratory tract infections with rapid onset of fever.