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HelpTest Code LABRXRM Transfusion Reaction, Whole Blood
Additional Codes
| Test Name in EPIC | EPIC Test Code | Mnemonic |
|---|---|---|
| Transfusion Reaction | LABRXRM | TXRX |
Test Alias
TXRX, trans react, transfusion, transfusion reaction, RXRM
Useful For/Utility
Pretransfusion compatibility testing begins with the type and screen procedure. The recipient’s ABO group and Rh type are determined first; then a screening procedure is used to detect any unexpected non-ABO blood group antibodies that may be present.
If the screening test reveals the presence of an antibody, the specificity of that antibody is determined by an antibody identification panel. Once the specificity of the antibody has been identified, donor units of the appropriate ABO group and Rh type are screened for the corresponding antigen. Units that are negative for that antigen are crossmatched with the recipient to ensure compatibility.
Methodology
Tube Testing/Gel Card Testing
Test Algorithm
If evidence of serologic incompatibility and extended workup will be performed, the pathologist notified immediately. If there is evidence of an acute hemolytic, microbial contamination, TRALI, or other serious complicantion of transfusion, the patients physician will be notified immediately by the pathologist. Reflex testing is ordered at the discretion of the pathologist.
Clinical Information
A transfusion is an irreversible event that carries potential benefits and risks to the patient. Hospitals must have a system for detection, reporting and evaluation of suspected complications of a transfusion. Transfusion Reactions include: transfusion associated circulatory overload (TACO), transfusion related acute lung injury (TRALI), transfuaion associated dyspnea (TAD), allergic (where severity is severe, life threatening, or death), hypotensive, febrile non-hemolytic, acute hemolytic, delayed hemolytic, transfusion associated graft vs host disease (TAGVHD), post-transfusion purpura (PTP), transfusion transmitted infection (TTI), urticaria (mild allergic), or other/unknown
Specimen Requirements
Specimen must arrive within 72 hours of draw.
Specimen Type: EDTA whole blood
Container/Tube: Pink top (K2EDTA)
Specimen Volume: 6 mL
Collection Instructions: Send specimen in original tube.
Additional Information:
1. Lavender-top (EDTA) tube is acceptable.
2. Instruct patient not to remove Blood Bank armband.
3. Label specimen for Blood Bank, see Transfusion Services in Special Instructions for labeling instructions.
Minimum Volume: Varies with patient condition. 1) For routine non-antibody patients, 2 mL of K2 EDTA whole blood. 2) In certain circumstances, additional blood may be requested to complete testing. If the patient has a known antibody, 2-3 6mL K2 EDTA whole blood tubes required.
Specimen Transport Temperature
Ambient/Refrigerate OK/Frozen NO
Day(s) Test Set Up
Upon request
Performing Laboratory
| Minnesota | North Dakota | Wisconsin |
|---|---|---|
| Deer River Hospital | Fargo Hospital | St. Mary's Hospital - Superior |
| Fosston Hospital | ||
| Holy Trinity Hospital (Graceville) | ||
| Moose Lake Hospital | ||
| Northern Pines (Aurora) | ||
| Sandstone Hospital | ||
| SMDC Clinical Lab (Duluth) | ||
| St. Joseph's Medical Center (Brainerd) | ||
| St. Mary's - Detroit Lakes Hospital | ||
| Virginia Hospital |
Special Instructions
Drawing instuctions can be obtained from the Source under the Resources tab. Select Policies & Procedures and Select Laboratory Releated Documents.