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Test Code LABSTRATJCV Stratify JCV Antibody (w/Index) w/Reflex to Inhibition Assay

Important Note

Clinical Significance

The JC Virus (JCV) is associated with progressive multifocal leukoencephalopathy (PML). Detection of antibodies to JCV in serum or plasma is a reliable indicator of exposure to JCV. The analytical performance characteristics were determined for multiple sclerosis patients.

Additional Codes

Test Name in EPIC EPIC Test Code Mnemonic

Stratify JCV Antibody (w/Index) w/Reflex to Inhibition Assay

 LABSTRATJCV STRATJCV

 

Methodology

Immunoassay (IA)

Specimen Requirements

Specimen Type:  Serum or EDTA Plasma

Collection Container/Tube: Plain Red top; Purple Top EDTA also acceptable

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL serum or EDTA plasma

Specimen Minimum Volume: 0.25 mL

Additional Information:

1. Reject due to gross hemolysis.

Specimen Transport Temperature

Ship room temp (stabile 7 days)

Day(s) Test Set Up

Tues-Sat

Report available:  1-4 days

Performing Laboratory

Quest Diagnostics, Incorporated

Test Classification and CPT Coding

86711

Reference Values

Reference Range:  Negative

If Index value is between 0.19 and 0.41 (not inclusive), JC Virus Antibody Inhibition Assay will be performed at an additional charge.

Index              Interpretative criteria

<0.20              Negative

0.20-0.40        Indeterminate

>0.40               Positive