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Test Code LABZINC ZINC, Serum or Plasma (ARUP)

Important Note

Patient Preparation
Diet, medication, and nutritional supplements may introduce interfering substances. Upon the advice of their physician, patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and nonessential over-the-counter medications for one week prior to sample draw

Additional Codes

Test Name in EPIC EPIC Test Code Mnemonic ARUP Test ID

ZINC, SERUM OR PLASMA (ARUP)

LABZINC ZINC 0020097

 

Useful For/Utility

May be useful as an indicator of acute deficiency.

Clinical Information

Elevated results may be due to skin or collection-related contamination, including the use of a noncertified metal-free collection/transport tube. If contamination concerns exist due to elevated levels of serum/plasma zinc, confirmation with a second specimen collected in a certified metal-free tube is recommended.

Circulating zinc concentrations are dependent on albumin status and are depressed with malnutrition.  Zinc may also be lowered with infection, inflammation, stress, oral contraceptives, and pregnancy.  Zinc may be elevated with zinc supplementation or fasting.  Elevated zinc concentrations may interfere with copper absorption.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes

 

Serum Zn levels are 16% higher that plasma Zn levels. Correctly assayed serum Zn levels can be converted to plasma by multiplying by 0.85.  Plasma Zn = 0.85 Serum Zn. Reference: Biochemistry of Zinc, Ananda S. Prasad, Plenum Press, New York and London, 1993.

 

Specimen Requirements

Royal Blue (K2 EDTA) - 2 mL

Separate from cells ASAP or within 2 hours of collection Transfer 2 mL serum or plasma to a Trace Element-Free Transport Tube

Specimen Type

Metal Free EDTA plasma, Metal Free serum acceptable

Specimen Preparation and Transport Temperature

 

Room temperature. Also acceptable: Refrigerated or frozen.

Unacceptable Conditions:  Specimens that are not separated from the red cells or clot within 2 hours. Specimens collected in containers other than specified. Specimens transported in containers other than specified. Hemolyzed specimens.

Reverence Values

60.0-120.0 µg/dL

Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry

Day(s) Set Up

Sunday  - Saturday

Reported:  1-3 days

LOINC and CPT Code Information

Component Test Code Component Chart Name LOINC
0020097 Zinc, Serum/Plasma 5763-8

CPT Code:  84630