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HelpTest Code PDSUX Drug Screen, Prescription/Over the Counter, Chain of Custody, Random, Urine
Useful For
Qualitative detection and identification of prescription or over-the-counter drugs frequently found in drug overdose or used with a suicidal intent
Providing, when possible, the identification of all drugs in the specimen
This test is not intended for use in employment-related testing.
This test is not intended for therapeutic compliance testing. The assay's limits of detection have been established for drugs at overdose levels, which are generally much higher than therapeutic concentrations.
This test is not useful for drugs of abuse or illicit drug testing, including benzodiazepines, opioids, barbiturates, cocaine, and amphetamine type stimulants.
Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by demonstrating that it was always under the control of personnel involved with testing the specimen; this control implies that the opportunity for specimen tampering would be limited.
Additional Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| COCH | Chain of Custody Processing | No | Yes |
Reporting Name
Drug Scrn, Prescription/OTC, CoC, USpecimen Type
UrineAdditional Testing Requirements
If urine creatinine is required or adulteration of the sample is suspected, also order, ADLTX / Adulterants Survey, Chain of Custody, Random, Urine.
Specimen Required
Supplies: Chain-of-Custody Kit (T282)
Container/Tube: Chain-of-Custody Kit containing the specimen containers, seals, and documentation required.
Specimen Volume: 30 mL
Collection Instructions: Collect a random specimen without preservative in the container provided, seal, and submit with the associated documentation to satisfy the legal requirements for chain-of-custody testing.
Additional Information: Submitting less than 30 mL will compromise the ability to perform all necessary testing.
Specimen Minimum Volume
1.1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days | ||
| Ambient | 3 hours |
Clinical Information
This test looks for a broad spectrum of prescription and over-the-counter drugs. It is designed to detect drugs that have toxic effects, as well as known antidotes or active therapies that a clinician can initiate to treat the toxic effect. The test is intended to help physicians manage an apparent overdose or intoxicated patient or to determine if a specific set of symptoms might be due to the presence of drugs. This test is not appropriate for drugs of abuse or illicit drug testing, including benzodiazepines, opioids, barbiturates, cocaine, and amphetamine type stimulants.
Drugs of toxic significance that are not detected by this test are digoxin, lithium, salicylate, and many drugs of abuse or illicit drugs, some benzodiazepines, and some opiates. For these drugs, see Mayo Clinic Laboratories' drug abuse surveys, drug screens, or individual tests.
Chain of custody is a record of the disposition of a specimen to document the personnel who collected, handled, and performed the analysis. When a specimen is submitted in this manner, analysis will be performed in such a way that it will withstand regular court scrutiny.
For detection limits for drugs detected in this test see Prescription and Over-the-Counter Drug Screening List and Limits of Detection.
Reference Values
Drugs detected are presumptive. Additional testing may be required to confirm the presence of any drugs detected.
Interpretation
The drugs that are detected by this test are listed in Prescription and Over-the-Counter Drug Screening List and Limits of Detection.
A detailed discussion of each drug detected is beyond the scope of this text. Each report will indicate the drugs identified. If a clinical interpretation is required, contact Mayo Clinic Laboratories at 800-533-1710 and ask to speak to a toxicology consultant.
Cautions
No significant cautionary statements
Method Description
Screening is by gas chromatography mass spectroscopy.(Unpublished Mayo method)
Day(s) Performed
Monday through Friday
Report Available
3 to 4 daysSpecimen Retention Time
2 weeksPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80307
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PDSUX | Drug Scrn, Prescription/OTC, CoC, U | 12286-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 36235 | Drugs detected: | 12286-1 |
| 36236 | Suspect Drug | No LOINC Needed |
| 36237 | Chain of Custody | 77202-0 |
Method Name
Gas Chromatography Mass Spectrometry (GC-MS)
Special Instructions
Forms
1. Chain of Custody Request is included in the Chain-of-Custody Kit (T282).
2. If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.